The DOE Joint Genome Institute (JGI) in Walnut Creek, CA (a division of the Lawrence Berkeley National Lab) has an exciting opportunity available for a Microbiome Postdoctoral Fellow. We are looking for a talented, highly motivated candidate with a strong background in microbial ecology and computational biology to expand the toolkit of sequence-to-function approaches for uncultivated microbial taxa. The successful candidate will be expected to design, benchmark, and apply bioinformatics and statistical tools to enable analysis and interpretation of stable isotope probing (SIP)-metagenomics data. The candidate will be expected to work independently, as well as contribute as a member of a dynamic, multidisciplinary team of biologists, bioinformaticians, computer scientists and software developers. The successful candidate will report directly to the Metagenome Program Head, but will work closely with the Microscale Applications Group Lead and production and scientific staff in the Prokaryote Super Program. Target start date of October 1, 2019.

What You Will Do:

  • Design, benchmark, and apply bioinformatics and statistical tools to enable analysis and interpretation of SIP-metagenomics data. Specifically, the candidate will develop a new SIP-metagenomics computational toolkit for the quantitative analysis of microbial groups actively assimilating isotopically-labeled compounds.

  • Apply knowledge of microbial metabolism and physiology to carry out in-depth characterization of isotopically-enriched microbial taxa across different experiments and environments

  • Gather feedback and requirements to develop software for the organization and handling of SIP-metagenomic data and automation of analytical procedures to deploy in a production setting

  • Work in a high-performance computing environment and interact with a team of computer scientists, software developers and postdoctoral researchers to develop new methods and statistical tools

  • Present updates at group meetings and at scientific conferences, and publish results in peer-reviewed journals

  • Contribute to research as part of a large multidisciplinary team

Additional Responsibilities as needed:

  • Support the development of visualization tools and/or user interface for navigation and data comparisons across SIP-metagenomic samples

What is Required:

  • Recent Ph.D. (within the last 4 years) in microbiology, bioinformatics, statistics or a related discipline

  • Substantial knowledge and understanding of bioinformatics tools for sequence similarity search, multiple sequence alignment, profile search, clustering and phylogenetic analyses using ribosomal genes and conserved marker genes is required

  • Significant experience in methods and tools for next-generation sequencing, metagenome assembly and binning, and genome reconstruction

  • Experience in a scripting language (Perl, Python) is a must, knowledge of Unix tools, relational databases and R is desirable

  • Excellent written and oral communication skills

  • Ability to independently carry out high-quality research with tenacity and creativity

  • Ability to troubleshoot complex systems and data analysis problems.

  • Demonstrated ability to conduct and perform collaborative research and effectively interact with a broad range of colleagues with tact and diplomacy.

  • Excellent organizational, analytical, and record-keeping skills with the ability to organize and present technical reports to collaborators, JGI staff, management, and sponsors.

  • Demonstrated ability to accurately and eloquently represent and promote scientific projects to audiences of diverse technical backgrounds.

Additional Desired Qualifications:

  • Experience in or familiarity with statistical analysis is desired

  • Experience in stable isotope probing (SIP) and associated data analysis is desirable, but not required

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Application deadline: Open until filled
Start date:
Location: Joint Genome Institute, Lawrence Berkeley National Laboratory, Berkeley, CA